Which is better to have, IUI or IVF? An excellent question. When considering fertility treatment choices, one of the first things people should do is compare intrauterine insemination (IUI) and in vitro fertilisation (IVF), as these are two of the most prevalent and effective reproductive therapies. But how can you know between IUI and IVF, which is the best option for you?
While it is always best to check with a medical professional before making any treatment decisions, this article is a great starting point for people trying to get pregnant with assisted reproductive technology (ART). For more on infertility treatment, call and book your appointment with World IVF, which is the Best fertility centre in Delhi.
IUI vs IVF: The Basics
The key distinction between IUI and IVF is the amount of eggs generated by the female and the location of fertilisation.
A woman is only meant to develop one or two eggs with an IUI. Sperms are implanted within the uterus, which gives the sperms an advantage, although natural fertilisation is still required.
In IVF, a woman is given more drugs in order to produce a large number of eggs. In an ideal world, they would produce roughly 15 mature eggs. The eggs are retrieved from the ovaries, fertilised and developed in a laboratory for a number of days, and then implanted as an early-stage embryo into the uterus. While this may appear to be a little variation, it leads to a significant number of notable differences.
Procedure for Treatment:
IUI: An IUI can be performed without any medicines or a variety of pharmaceuticals to assist in the development and ovulation of one or two eggs. Insemination occurs around day 14 of a woman’s cycle, depositing sperm inside the uterus. This dramatically increases the quantity of the sperm at the uterus-fallopian tube junction, the distance they must swim to meet the egg, and hence, increasing the chances of natural conception for many people.
IVF: During IVF, drugs are often administered for 10 days in order to produce a significant number of eggs. Once a large number of eggs have formed, the eggs are extracted from the ovaries. The eggs are then fertilised in a laboratory outside of the body. After a few days of growth in the lab, an embryo is placed back into the woman’s uterus.
How do they overcome infertility?
An IUI aids in the treatment of infertility in two ways.
Egg quality and ovulation: Medications are used to assist in the growth and ovulation of one or two mature eggs (some women may not ovulate otherwise).
Sperm quality: An IUI brings sperm significantly closer to its intended destination (the egg). IUI can multiply the quantity of sperms that reach the fallopian tube by a factor of 1000.
IVF beats infertility in MANY ways:
Ovulation: eggs are collected before ovulation.
Tubal problems occur when eggs are taken from the ovaries and embryos are transferred directly into the uterus, fully skipping the tubes.
Sperm: One healthy sperm is all that is required for intracytoplasmic sperm injection (ICSI), a procedure that directly injects sperm into the egg.
Uterine: A variety of drugs can be used to improve uterine receptivity and the timing of embryo transfers.
Miscarriage: Both genetic testing and reproductive immunology can be used in conjunction with IVF to lower the risk of miscarriage in some cases.
Quality and quantity of eggs: Big doses of drugs mature a large number of eggs, mature eggs, which are high-quality eggs.
IVF can also be used for elective purposes like as sex selection (where law permits).
Both methods are mostly safe but pose few hazards. Proper monitoring, medicine selection and dose, and overall care can all help to limit risks and negative effects.
IVF necessitates “surgery” while under anaesthesia, whereas IUI does not.
General Treatment Sequence:
Because IUI is less intrusive, it is usually tried first if the diagnostic allows before moving to the more invasive IVF process.
There are numerous illnesses that make IUI contraindication. If a patient has blocked tubes, severe male factor infertility, or a number of other male or female factors, a fertility physician may advocate proceeding directly to in vitro fertilisation because IVF works around significantly more infertility producing issues than IUI.
When is the best time to get pregnant?
Because of its increased success rate per cycle, IVF has a substantially shorter time to pregnancy. Success rates for persons under the age of 35 are typically about 50% per therapy.
In general, IUIs have a success rate of 5-20% per cycle. If an IUI is effective, it usually occurs during the first three or four treatment cycles.
The costs of IUI and IVF vary substantially and are determined by a variety of factors.
On a per-cycle basis, IUI is much less expensive.
On a per-birth basis, the situation is a little murkier. IUIs may be a poor option for some people (such as those with clogged tubes), reducing their chances of having a child to near nil. Furthermore, after three IUI cycles, the chances of any following cycle succeeding are low, and IVF becomes considerably more inexpensive on a per-birth basis.
IUI and IVF Treatment Options
Before we go any further, it’s vital to note that there are numerous varieties of IUI and IVF. While they are members of the same treatment “family,” there are significant distinctions and variations that must be acknowledged.
There are several forms of insemination based on where the sperm is deposited, and four types of IUI cycles based on the drugs used in the treatment. Your preferences, fertility diagnostic testing, and medical history all play a role in determining which sort of IUI cycle is best for you.
Different types of insemination are based on where the sperm is put.
Artificial inseminations are classified into two types:
IVI/ICI: Intra (vaginal/cervical) Insemination is a procedure that can be performed in a medical office or at home. An IVI involves depositing sperm with a syringe at the top of the vagina, as close to the cervix as feasible. NOT INTRAUTERINE INSEMINATION, but a type of artificial insemination.
IUI: Intrauterine Insemination is only performed in a medical setting, such as an OBGYN office or a Fertility Clinic. The sperm is “washed,” concentrated, and placed into a catheter that is passed through the cervix and deposited near the top of the uterus during an IUI.
Depending on the drug used, there are various types of IUI.
Natural cycle – A natural IUI cycle does not include the use of any drugs.
Trigger cycle – This adds the component of taking medication to trigger ovulation at a certain time to better the timing of insemination, improving the chances of conception. IUI usually takes place 12 to 36 hours after the trigger drug has been administered orally or intravenously.
Clomid or letrozole is administered orally to stimulate egg growth and ovulation. Oral drugs also have a lower risk of multiples as compared to injectables.
Cycle of injectable gonadotropin medicines – Injectable gonadotropin medications stimulate the ovaries more than the oral medications. As a result, the chance of multiples is higher with injectables.
Regardless of the type of IUI cycle you choose, your cycle will be tracked either through regular blood work and ultrasounds or at home with an ovulation prediction kit. If you are using drugs throughout your IUI cycle, you will most likely be monitored with bloodwork and ultrasounds to guarantee follicular growth and a safe and effective cycle.
The easiest approach to grasp the many types of IVF is to realise that IVF is an umbrella word used to describe a treatment in which fertilisation occurs outside of the body. Differences can be attributed to drugs, fertilisation, embryo “processing,” and the location of conception. Different types can also be blended.
Fertilization Technique – Conventional IVF: The earliest fertilisation procedure developed. Sperm is inserted in a petri dish to fertilise the egg through self-employed penetration.
ICSI IVF – Fertilization Procedure: IVF using a one-of-a-kind fertilisation technique in which sperm is put into a microneedle and inserted directly into the egg.
Mini IVF – Medication Regimen: IVF using a reduced medication protocol to recruit fewer, but hopefully still more than one quality egg.
Natural IVF – Medication Protocol: An IVF cycle in which no pharmaceuticals are utilised to increase the number of eggs produced. Only one (or, in exceptional cases, two) egg can be retrieved.
FET IVF – Embryo Processing: The transfer of an IVF cycle’s previously frozen and thawed embryo.
INVOcell – Fertilization Location: A method of fertilisation in which sperm and egg are deposited in a thumb-sized medical device that is introduced into the vagina for fertilisation and early development. The procedure is identical to conventional fertilisation, except that it takes place in a vaginal device rather than an incubator at an embryology lab. Schedule your appointment for infertility treatment with World IVF hospital in Lajpat nagar.